Progeskin
Short introduction to Progeskin
The aging of the skin is a complex process involving several key proteins, including progerin and the Klotho protein. Progerin is present in higher concentrations in aging cells and triggers a phenomenon known as senescence, or cellular aging. This process can be simplistically described as a state where cells stop dividing but continue to live like zombie cells. As these cells increase in number, the quality of the tissue and its ability to repair itself and maintain its function are affected. This is when lines and wrinkles appear.
The Klotho protein is a youth protein that strengthens and promotes the function and lifespan of cells. This protein acts as an anti-aging factor by strengthening the cell nuclei and enhancing cellular communication. It has several positive properties, including important protection against oxidative stress that prevents cells from aging prematurely.
Progeskin is a groundbreaking dual-action serum with two main ingredients that are entirely new to the skincare world. Progescence® is a tripeptide that reduces the production of progerin and stimulates the skin's ability to produce collagen and synthesize rejuvenating proteins. The skin becomes smoother, firmer, and more elastic.
Pro-KL® provides the truly rejuvenating effect by activating the Klotho protein. Skin cells are infused with vitality and achieve a regulated metabolism, which in turn delays cellular aging. This ingredient restores the skin's ability to regenerate itself and protects it from premature aging.
Dive into Progeskin in detail by scrolling down!
Read more and get to know the background of Progeskin and how aging affects the skin.
The aging of the skin begins with senescence
A natural phenomenon
Senescence can also be triggered by factors such as cellular stress or genetic mutations, resulting in premature aging. Over time, these inactive "zombie cells" accumulate, significantly contributing to aging skin and age-related diseases, as well as the appearance of visible age-related signs on the skin. This often manifests as thinner skin where the various layers lose their structure, wrinkles, loss of elasticity, and pigmentation.
Two proteins in focus
The other protein, the Klotho protein, is the opposite of progerin. Its name comes from ancient Greece, Clotho, a goddess who spun the thread of life. This protein enhances and extends the vitality of cells and protects them against oxidative stress. On a more advanced level, the Klotho protein plays a key role in ensuring strong signaling pathways that regulate metabolic activities. It also has an inhibitory effect on insulin receptors and promotes antioxidants to counteract oxidative stress and increase the cell's own resistance to aging. These properties are highly beneficial for promoting cell longevity. Here too, there is an important biomarker, as a healthy and fully functioning Klotho protein has a reducing effect on many types of tumors.
What does the Klotho protein do for the skin?
It acts in four ways:-
Protection against oxidative stress at the cellular level. This type of stress is known to cause damage that leads to premature aging of the skin.
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Preservation of the skin barrier by strengthening the bond between epidermal cells. With strong protection, the skin is less prone to drying out and more resilient. It should be noted that the Klotho protein complements other mechanisms for this effect.
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Stimulation of cell renewal by enhancing the communication pathways within cells that promote cell health. This helps the skin remain smooth and radiant.
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Enhanced collagen production by detoxifying the cells and stimulating their activity.
Introducing Progeskin
In developing Progeskin, the focus has been on the cellular aging of the skin and its various phases. As we have already established, senescence is the true trigger for aging. The revolutionary aspect of Progeskin is that it provides the skin with the necessary tools to act in time to repair damage and strengthen its biochemical resilience to stay healthy.
Two groundbreaking ingredients
The serum contains Progesence®, a patented tripeptide that reduces the synthesis of progerin. The result after regular use is smoother and firmer skin with a rejuvenated appearance. Progesence® boosts the skin's ability to produce collagen and other vital proteins that play a key role in cell renewal.
As a strong complement to Progesence®, Pro-KL® has been developed with exceptional anti-aging properties. This ingredient activates the Klotho protein, which we know is a crucial factor for cell vitality. The ingredient restructures and regenerates the skin by strengthening the connective tissue and the bonds between cells.
What our tests tells us
Ex-vivo test results
- A significant reduction in progerin by -26.6%
- In untreated skin, progerin levels corresponded to an age of 51.9 years.
- On treated skin, progerin levels corresponded to an age of 39.2 years.
- This means a rejuvenation of the epidermis by 12.7 years.
The tests were conducted after 10 days of treatment. Untreated skin was compared with treated skin to measure the results.
In-vivo test results
- Measurements showed an 11% improvement in elasticity after 28 days, and an additional 23% increase in elasticity after 56 days.
- Elasticity was also measured, showing a 17% improvement after 28 days and an additional 19% after 56 days.
The tests were conducted on 21 women aged 45-69. They used the product twice a day for a period of 56 days.
How to apply the serum
Thoroughly cleanse the skin. Apply a few drops over the entire face, neck, and décolletage. Gently pat the serum in with light, upward motions until fully absorbed. Follow with the recommended skincare routine as advised by your Skin Expert.
